Population genetic structure and natural selection of Plasmodium falciparum apical membrane antigen-1 in Myanmar isolates

Population genetic structure and natural selection of Plasmodium falciparum apical membrane antigen-1 in Myanmar isolates

Abstract Background Plasmodium falciparum apical membrane antigen-1 (PfAMA-1) is one of leading blood stage malaria vaccine candidates. However, genetic variation and antigenic diversity identified in global PfAMA-1 are major hurdles in the development of an effective vaccine based on this antigen....

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Bibliographic Details
Main Authors: Jung-Mi Kang, Jinyoung Lee, Mya Moe, Hojong Jun, Hương Giang Lê, Tae Im Kim, Thị Lam Thái, Woon-Mok Sohn, Moe Kyaw Myint, Khin Lin, Ho-Joon Shin, Tong-Soo Kim, Byoung-Kuk Na
Format: Article
Language:English
Published: BMC 2018-02-01
Series:Malaria Journal
Subjects:
Plasmodium falciparum
Apical membrane antigen-1
Genetic diversity
Natural selection
Myanmar
Online Access:http://link.springer.com/article/10.1186/s12936-018-2215-7

Internet

http://link.springer.com/article/10.1186/s12936-018-2215-7

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