Multimodal Analysis of STRADA Function in Brain Development

Multimodal Analysis of STRADA Function in Brain Development

mTORopathies are a heterogeneous group of neurological disorders characterized by malformations of cortical development (MCD), enhanced cellular mechanistic target of rapamycin (mTOR) signaling, and epilepsy that results from mutations in mTOR pathway regulatory genes. Homozygous mutations (del exon...

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Bibliographic Details
Main Authors: Louis T. Dang, Katarzyna M. Glanowska, Philip H. Iffland II, Allan E. Barnes, Marianna Baybis, Yu Liu, Gustavo Patino, Shivanshi Vaid, Alexandra M. Streicher, Whitney E. Parker, Seonhee Kim, Uk Yeol Moon, Frederick E. Henry, Geoffrey G. Murphy, Michael Sutton, Jack M. Parent, Peter B. Crino
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Cellular Neuroscience
Subjects:
mTOR
megalencephaly
epilepsy
iPSC
mouse
seizure
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2020.00122/full

Internet

https://www.frontiersin.org/article/10.3389/fncel.2020.00122/full

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