Human CD56+ cytotoxic lung lymphocytes kill autologous lung cells in chronic obstructive pulmonary disease.

CD56+ natural killer (NK) and CD56+ T cells, from sputum or bronchoalveolar lavage of subjects with chronic obstructive pulmonary disease (COPD) are more cytotoxic to highly susceptible NK targets than those from control subjects. Whether the same is true in lung parenchyma, and if NK activity actua...

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Bibliographic Details
Main Authors: Christine M Freeman, Valerie R Stolberg, Sean Crudgington, Fernando J Martinez, MeiLan K Han, Stephen W Chensue, Douglas A Arenberg, Catherine A Meldrum, Lisa McCloskey, Jeffrey L Curtis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4117545?pdf=render