Targeting the NLRP3 inflammasome to attenuate spinal cord injury in mice

Abstract Background Spinal cord injury (SCI) is a devastating disease, which results in tissue loss and neurologic dysfunction. NLRP3 inflammasome plays an important role in the mechanism of diverse diseases. However, no studies have demonstrated the role of NLRP3 inflammasome and the effects of NLR...

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Bibliographic Details
Main Authors: Wu Jiang, Maoqiang Li, Fan He, Shaobo Zhou, Liulong Zhu
Format: Article
Language:English
Published: BMC 2017-10-01
Series:Journal of Neuroinflammation
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12974-017-0980-9