Snf1 cooperates with the CWI MAPK pathway to mediate the degradation of Med13 following oxidative stress

Snf1 cooperates with the CWI MAPK pathway to mediate the degradation of Med13 following oxidative stress

Eukaryotic cells, when faced with unfavorable environmental conditions, mount either pro-survival or pro-death programs. The conserved cyclin C-Cdk8 kinase plays a key role in this decision. Both are members of the Cdk8 kinase module that, along with Med12 and Med13, associate with the core Mediator...

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Bibliographic Details
Main Authors: Stephen D. Willis, David C. Stieg, Kai Li Ong, Ravina Shah, Alexandra K. Strich, Julianne H. Grose, Katrina F. Cooper
Format: Article
Language:English
Published: Shared Science Publishers OG 2018-06-01
Series:Microbial Cell
Subjects:
cyclin C
Cdk8
Med13
SCFGrr1
AMPK
Snf1
ubiquitin mediated destruction
signal transduction
H2O2 stress
MAPK
Online Access:http://microbialcell.com/researcharticles/snf1-cooperates-with-the-cwi-mapk-pathway-to-mediate-the-degradation-of-med13-following-oxidative-stress/

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http://microbialcell.com/researcharticles/snf1-cooperates-with-the-cwi-mapk-pathway-to-mediate-the-degradation-of-med13-following-oxidative-stress/

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