Two-Component-System RspA1/A2-Dependent Regulation on Primary Metabolism in Streptomyces albus A30 Cultivated With Glutamate as the Sole Nitrogen Source

Two-Component-System RspA1/A2-Dependent Regulation on Primary Metabolism in Streptomyces albus A30 Cultivated With Glutamate as the Sole Nitrogen Source

In our previous study, a two-component-system (TCS) RspA1/A2 was identified and proven to play a positive role in the regulation of salinomycin (antibiotic) biosynthesis in Streptomyces albus. However, the regulatory mechanism of RspA1/A2 using a carbon source (glucose or acetate) for the cell growt...

Full description

Bibliographic Details
Main Authors: Kuipu Zhang, Ali Mohsin, Junxiong Yu, Yuwen Hu, Muhammad Fahad Ali, Zhongbing Chen, Yingping Zhuang, Ju Chu, Meijin Guo
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Microbiology
Subjects:
two-component system
phosphoenolpyruvate-pyruvate-oxaloacetate node
gluconeogenesis
Streptomyces albus
glucose consumption rate
transcriptome analysis
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2020.01658/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2020.01658/full

Similar Items