Promoter hypermethylation-mediated inactivation of multiple Slit-Robo pathway genes in cervical cancer progression

<p>Abstract</p> <p>Background</p> <p>Cervical Cancer (CC) exhibits highly complex genomic alterations. These include hemizygous deletions at 4p15.3, 10q24, 5q35, 3p12.3, and 11q24, the chromosomal sites of Slit-Robo pathway genes. However, no candidate tumor suppressor...

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Bibliographic Details
Main Authors: Mansukhani Mahesh, Dürst Matthias, Schneider Achim, Kaufmann Andreas M, Arias-Pulido Hugo, Goparaju Chandra, Narayan Gopeshwar, Pothuri Bhavana, Murty Vundavalli V
Format: Article
Language:English
Published: BMC 2006-05-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/5/1/16