Evidence of Progenitor Cell Lineage Rerouting in the Adult Mouse Hippocampus After Status Epilepticus

Evidence of Progenitor Cell Lineage Rerouting in the Adult Mouse Hippocampus After Status Epilepticus

Cell lineage in the adult hippocampus comprises multipotent and neuron-committed progenitors. In the present work, we fate-mapped neuronal progenitors using Dcx-CreERT2 and CAG-CAT-EGFP double-transgenic mice (cDCX/EGFP). We show that 3 days after tamoxifen-mediated recombination in cDCX/EGFP adult...

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Bibliographic Details
Main Authors: Daniela M. S. Moura, Juliana Alves Brandão, Celia Lentini, Christophe Heinrich, Claudio M. Queiroz, Marcos R. Costa
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Neuroscience
Subjects:
adult hippocampus
neurogenesis
astrogliogenesis
status epilepticus
fate-specification
kainic acid
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2020.571315/full

Internet

https://www.frontiersin.org/article/10.3389/fnins.2020.571315/full

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