Generation and physiological roles of linear ubiquitin chains

<p>Abstract</p> <p>Ubiquitination now ranks with phosphorylation as one of the best-studied post-translational modifications of proteins with broad regulatory roles across all of biology. Ubiquitination usually involves the addition of ubiquitin chains to target protein molecules,...

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Bibliographic Details
Main Authors: Walczak Henning, Iwai Kazuhiro, Dikic Ivan
Format: Article
Language:English
Published: BMC 2012-03-01
Series:BMC Biology
Online Access:http://www.biomedcentral.com/1741-7007/10/23