A new and clinically relevant murine model of solid-organ transplant aspergillosis

SUMMARY Invasive fungal infections (IFIs) are a major cause of death in organ transplant patients. The murine hydrocortisone-mediated immunosuppression model of pulmonary aspergillosis is commonly used to characterise IFIs in these patients. However, this model does not take into account the effects...

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Bibliographic Details
Main Authors: Susanne Herbst, Anand Shah, Martin Carby, Gary Chusney, Naresh Kikkeri, Anthony Dorling, Elaine Bignell, Sunil Shaunak, Darius Armstrong-James
Format: Article
Language:English
Published: The Company of Biologists 2013-05-01
Series:Disease Models & Mechanisms
Online Access:http://dmm.biologists.org/content/6/3/643