Applying hydrodynamic pressure to efficiently generate induced pluripotent stem cells via reprogramming of centenarian skin fibroblasts.

Applying hydrodynamic pressure to efficiently generate induced pluripotent stem cells via reprogramming of centenarian skin fibroblasts.

Induced pluripotent stem cell (iPSC)-technology is an important platform in medicine and disease modeling. Physiological degeneration and disease onset are common occurrences in the aging population. iPSCs could offer regenerative medical options for age-related degeneration and disease in the elder...

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Bibliographic Details
Main Authors: Massoud Vosough, Francesco Ravaioli, Mihaela Zabulica, Miriam Capri, Paolo Garagnani, Claudio Franceschi, Julie Piccand, Marine R-C Kraus, Kristina Kannisto, Roberto Gramignoli, Stephen C Strom
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0215490

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https://doi.org/10.1371/journal.pone.0215490

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