Effect of local administration of cyclosporine A on peripheral nerve regeneration in a rat sciatic nerve transection model
【Abstract】Objective: To assess the effect of cyclosporine A (CsA) loaded in chitosan conduit on bridging the sciatic nerve defects in a rat model. Methods: A 10 mm sciatic nerve defect was bridged using a chitosan conduit filled with 10 µl carrier-drug dilu- tion (10 µg/L CsA). In control group, t...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2014-02-01
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Series: | Chinese Journal of Traumatology |
Online Access: | http://www.cjtrauma.com/apps/ojs/index.php/cjt/article/view/488 |