Effect of local administration of cyclosporine A on peripheral nerve regeneration in a rat sciatic nerve transection model

【Abstract】Objective: To assess the effect of cyclosporine A (CsA) loaded in chitosan conduit on bridging the sciatic nerve defects in a rat model. Methods: A 10 mm sciatic nerve defect was bridged using a chitosan conduit filled with 10 µl carrier-drug dilu- tion (10 µg/L CsA). In control group, t...

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Bibliographic Details
Main Authors: Mohammadi Rahim, Heydarian Hadi, Amini Keyvan
Format: Article
Language:English
Published: Elsevier 2014-02-01
Series:Chinese Journal of Traumatology
Online Access:http://www.cjtrauma.com/apps/ojs/index.php/cjt/article/view/488