Tridimensional Retinoblastoma Cultures as Vitreous Seeds Models for Live-Cell Imaging of Chemotherapy Penetration

Tridimensional Retinoblastoma Cultures as Vitreous Seeds Models for Live-Cell Imaging of Chemotherapy Penetration

A preclinical model could aid in understanding retinoblastoma vitreous seeds behavior, drug penetration, and response to chemotherapy to optimize patient treatment. Our aim was to develop a tridimensional in vitro model of retinoblastoma vitreous seeds to assess chemotherapy penetration by means of...

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Bibliographic Details
Main Authors: Ursula Winter, Rosario Aschero, Federico Fuentes, Fabian Buontempo, Santiago Zugbi, Mariana Sgroi, Claudia Sampor, David H. Abramson, Angel M. Carcaboso, Paula Schaiquevich
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:International Journal of Molecular Sciences
Subjects:
tumorspheres
retinoblastoma
topotecan
penetration
confocal microscopy
Online Access:http://www.mdpi.com/1422-0067/20/5/1077

Internet

http://www.mdpi.com/1422-0067/20/5/1077

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