Base-free enantioselective SN2 alkylation of 2-oxindoles via bifunctional phase-transfer catalysis

N-Protected oxindole derivatives of unprecedented malleability bearing ester moieties at C-3 have been shown to participate in enantioselective phase-transfer-catalysed alkylations promoted by ad-hoc designed quaternary ammonium salts derived from quinine bearing hydrogen-bond donating substituents....

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Bibliographic Details
Main Authors: Mili Litvajova, Emiliano Sorrentino, Brendan Twamley, Stephen J. Connon
Format: Article
Language:English
Published: Beilstein-Institut 2021-09-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
Online Access:https://doi.org/10.3762/bjoc.17.146