Human Umbilical Cord Blood-Derived Monocytes Improve Cognitive Deficits and Reduce Amyloid-β Pathology in PSAPP Mice

Alzheimer's disease (AD) is the fourth major cause of mortality in the elderly in the US and the leading cause of dementia worldwide. While pharmacological targets have been discovered, there are no true disease-modifying therapies. We have recently discovered that multiple low-dose infusions o...

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Bibliographic Details
Main Authors: Donna Darlington, Song Li, Huayan Hou, Ahsan Habib, Jun Tian, Yang Gao, Jared Ehrhart, Paul R Sanberg, Darrell Sawmiller, Brian Giunta, Takashi Mori, Jun Tan
Format: Article
Language:English
Published: SAGE Publishing 2015-11-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/096368915X688894