Engineering of TM1459 from Thermotoga maritima for increased oxidative alkene cleavage activity

Oxidative cleavage of alkenes is a widely employed process allowing oxyfunctionalization to corresponding carbonyl compounds. Recently, a novel biocatalytic oxidative alkene cleavage activity on styrene derivatives was identified in TM1459 from Thermotoga maritima. In this work we engineered the enz...

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Bibliographic Details
Main Authors: Matthias Fink, Sarah Trunk, Mélanie Hall, Helmut Schwab, Kerstin Steiner
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-09-01
Series:Frontiers in Microbiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2016.01511/full