A proposed molecular mechanism for pathogenesis of severe RNA-viral pulmonary infections [version 1; peer review: 2 approved]
Background: Certain riboviruses can cause severe pulmonary complications leading to death in some infected patients. We propose that DNA damage induced-apoptosis accelerates viral release, triggered by depletion of host RNA binding proteins (RBPs) from nuclear RNA bound to replicating viral sequence...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
F1000 Research Ltd
2020-08-01
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| Series: | F1000Research |
| Online Access: | https://f1000research.com/articles/9-943/v1 |