Leishmania braziliensis-reactive T cells are down-regulated in long-term cured cutaneous Leishmaniasis, but the renewal capacity of T effector memory compartments is preserved.

Leishmania braziliensis-reactive T cells are down-regulated in long-term cured cutaneous Leishmaniasis, but the renewal capacity of T effector memory compartments is preserved.

Leishmania (Viannia) braziliensis control and tissue damage relate to the effector immune response, which in turn affects clinical outcome. Leishmania reactive CD4(+) and CD8(+) T cells are expanded in long-term healed cutaneous leishmaniasis (hCL) patients but their functional characteristics remai...

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Bibliographic Details
Main Authors: Regina Pereira-Carvalho, Carolina O Mendes-Aguiar, Manoel P Oliveira-Neto, Cláudia J F Covas, Alvaro L Bertho, Alda M Da-Cruz, Adriano Gomes-Silva
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3841203?pdf=render

Internet

http://europepmc.org/articles/PMC3841203?pdf=render

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