Arg-Gly-Asp-modified elastin-like polypeptide regulates cell proliferation and cell cycle proteins via the phosphorylation of Erk and Akt in pancreatic β-cell

Arg-Gly-Asp-modified elastin-like polypeptide regulates cell proliferation and cell cycle proteins via the phosphorylation of Erk and Akt in pancreatic β-cell

Objective: Enhancement of β-cell proliferation plays an important role in maintaining β-cell mass and function, and in improving pancreatic β-cell survival before transplantation. Extracellular matrix (ECM) components increase the adhesion and proliferation of β-cells, and the RGD-modified elastin-l...

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Bibliographic Details
Main Authors: Yeo Jin Hwang, Gwon-Soo Jung, Won Bae Jeon, Kyeong-Min Lee
Format: Article
Language:English
Published: Elsevier 2020-09-01
Series:Heliyon
Subjects:
Tissue engineering
Biomedical materials
Cell biology
Biotechnology
Diabetes
Insulin
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844020317618

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http://www.sciencedirect.com/science/article/pii/S2405844020317618

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