Reduced Let-7a Is Associated with Chemoresistance in Primary Breast Cancer.

Chemotherapy resistance remains an important problem in the breast cancer clinic. The ability to predict the patients who would respond to a distinct therapy would help to optimize tailored treatment options. miRNAs can mediate a number of genes in response to drug-induced acute cellular stress. Sev...

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Bibliographic Details
Main Authors: Jiannan Wu, Shunrong Li, Weijuan Jia, Heran Deng, Kai Chen, Liling Zhu, Fengyan Yu, Fengxi Su
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4517895?pdf=render