Bioassay-Guided Isolation of Nigracin, Responsible for the Tissue Repair Properties of Drypetes Klainei Stem Bark

Drypetes klainei Pierre ex Pax is used in Cameroon by Baka people in the wound healing process and for the treatment of burns. In a previous paper we demonstrated the ability of both water (WE) and defatted methanol (DME) extracts to accelerate scratch wound closure in fibroblast cultures, thus vali...

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Main Authors: Gianluca Sferrazza, Marco Corti, Federica Andreola, Daniela Giovannini, Giuseppe Nicotera, Manuela Zonfrillo, Massimo Serra, Sara Tengattini, Enrica Calleri, Gloria Brusotti, Pasquale Pierimarchi, Annalucia Serafino
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-01-01
Series:Frontiers in Pharmacology
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Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.01541/full