High multiple mutations of Plasmodium falciparum-resistant genotypes to sulphadoxine-pyrimethamine in Lagos, Nigeria

High multiple mutations of Plasmodium falciparum-resistant genotypes to sulphadoxine-pyrimethamine in Lagos, Nigeria

Abstract Background Plasmodium falciparum-resistance to sulphadoxine-pyrimethamine (SP) has been largely reported among pregnant women. However, the profile of resistance markers to SP dihydrofolate reductase (dhfr) and dihydropteroate synthase (dhps) in the general population are varied and not fre...

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Bibliographic Details
Main Authors: Hong Quan, Uche Igbasi, Wellington Oyibo, Sunday Omilabu, Shen-Bo Chen, Hai-Mo Shen, Chukwuma Okolie, Jun-Hu Chen, Xiao-Nong Zhou
Format: Article
Language:English
Published: BMC 2020-07-01
Series:Infectious Diseases of Poverty
Subjects:
Plasmodium falciparum
Antimalarial drug resistance
Sulphadoxine–pyrimethamine
Dihydrofolate reductase
Dihydropteroate synthase
Online Access:http://link.springer.com/article/10.1186/s40249-020-00712-4

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http://link.springer.com/article/10.1186/s40249-020-00712-4

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