Complex genetic architecture of cardiac disease in a wild type inbred strain of Drosophila melanogaster.

Natural populations of the fruit fly, Drosophila melanogaster, segregate genetic variation that leads to cardiac disease phenotypes. One nearly isogenic line from a North Carolina peach orchard, WE70, is shown to harbor two genetically distinct heart phenotypes: elevated incidence of arrhythmias, an...

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Bibliographic Details
Main Authors: Zhi Zhang, Benjamin Hsieh, Amy Poe, Julie Anderson, Karen Ocorr, Greg Gibson, Rolf Bodmer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3639251?pdf=render