A simple self-maintaining metabolic system: robustness, autocatalysis, bistability.

A living organism must not only organize itself from within; it must also maintain its organization in the face of changes in its environment and degradation of its components. We show here that a simple (M,R)-system consisting of three interlocking catalytic cycles, with every catalyst produced by...

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Bibliographic Details
Main Authors: Gabriel Piedrafita, Francisco Montero, Federico Morán, María Luz Cárdenas, Athel Cornish-Bowden
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC2916848?pdf=render