Effects of Dl-3-n-butylphthalide on Cerebral Ischemia Infarction in Rat Model by Mass Spectrometry Imaging

Effects of Dl-3-n-butylphthalide on Cerebral Ischemia Infarction in Rat Model by Mass Spectrometry Imaging

Dl-3-n-butylphthalide (NBP) is a drug that is used in the treatment of ischaemic stroke. However, to the best of our knowledge, there are no systematic studies investigating the effects of dl-3-n-butylphtalide on the brain metabolism of small molecules. In this study, we first investigated the effec...

Full description

Bibliographic Details
Main Authors: Run-Zhe Liu, Chao-Xin Fan, Zhi-Lin Zhang, Xin Zhao, Yi Sun, Hui-Hui Liu, Zong-Xiu Nie, Xiao-Ping Pu
Format: Article
Language:English
Published: MDPI AG 2017-11-01
Series:International Journal of Molecular Sciences
Subjects:
dl-3-n-butylphthalide
permanent middle cerebral artery occlusion (pMCAO)
matrix-assisted laser desorption time of flight ionization mass spectrometry imaging (MALDI–TOF–MS imaging)
metabolites
Online Access:https://www.mdpi.com/1422-0067/18/11/2451

Internet

https://www.mdpi.com/1422-0067/18/11/2451

Similar Items