Scandoside Exerts Anti-Inflammatory Effect Via Suppressing NF-κB and MAPK Signaling Pathways in LPS-Induced RAW 264.7 Macrophages

Scandoside Exerts Anti-Inflammatory Effect Via Suppressing NF-κB and MAPK Signaling Pathways in LPS-Induced RAW 264.7 Macrophages

The iridoids of Hedyotis diffusa Willd play an important role in the anti-inflammatory process, but the specific iridoid with anti-inflammatory effect and its mechanism has not be thoroughly studied. An iridoid compound named scandoside (SCA) was isolated from H. diffusa and its anti-inflammatory ef...

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Bibliographic Details
Main Authors: Jingyu He, Jiafeng Li, Han Liu, Zichao Yang, Fenghua Zhou, Ting Wei, Yaqian Dong, Hongjiao Xue, Lan Tang, Menghua Liu
Format: Article
Language:English
Published: MDPI AG 2018-02-01
Series:International Journal of Molecular Sciences
Subjects:
scandoside
nuclear transcription factor kappa-B alpaha
mitogen-activated protein kinase
anti-inflammation
Online Access:http://www.mdpi.com/1422-0067/19/2/457

Internet

http://www.mdpi.com/1422-0067/19/2/457

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