Establishment of human induced trophoblast stem-like cells from term villous cytotrophoblasts

Establishment of human induced trophoblast stem-like cells from term villous cytotrophoblasts

Human trophoblast stem cells (hTSC) can be isolated from first trimester placenta but not from term placenta. Here we demonstrate that villous cytotrophoblasts (vCTB) from term placenta can be reprogrammed into induced trophoblastic stem-like cells (iTSC) by introducing sets of transcription factors...

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Bibliographic Details
Main Authors: Tao Bai, Chian-Yu Peng, Ivy Aneas, Noboru Sakabe, Daniela F. Requena, Christine Billstrand, Marcelo Nobrega, Carole Ober, Mana Parast, John A. Kessler
Format: Article
Language:English
Published: Elsevier 2021-10-01
Series:Stem Cell Research
Subjects:
Placenta
Trophoblast
Stem cell
Reprogramming
Differentiation
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506121003548

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http://www.sciencedirect.com/science/article/pii/S1873506121003548

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