Effect of P2X7 receptor knockout on AQP-5 expression of type I alveolar epithelial cells.

P2X7 receptors, ATP-gated cation channels, are specifically expressed in alveolar epithelial cells. The pathophysiological function of this lung cell type, except a recently reported putative involvement in surfactant secretion, is unknown. In addition, P2X7 receptor-deficient mice show reduced infl...

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Bibliographic Details
Main Authors: Georg Ebeling, Robert Bläsche, Falk Hofmann, Antje Augstein, Michael Kasper, Kathrin Barth
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4062497?pdf=render