Statistical resolution of ambiguous HLA typing data.

High-resolution HLA typing plays a central role in many areas of immunology, such as in identifying immunogenetic risk factors for disease, in studying how the genomes of pathogens evolve in response to immune selection pressures, and also in vaccine design, where identification of HLA-restricted ep...

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Bibliographic Details
Main Authors: Jennifer Listgarten, Zabrina Brumme, Carl Kadie, Gao Xiaojiang, Bruce Walker, Mary Carrington, Philip Goulder, David Heckerman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-02-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC2289775?pdf=render