DNA Copy Number Variation Associated with Anti-tumour Necrosis Factor Drug Response and Paradoxical Psoriasiform Reactions in Patients with Moderate-to-severe Psoriasis

DNA Copy Number Variation Associated with Anti-tumour Necrosis Factor Drug Response and Paradoxical Psoriasiform Reactions in Patients with Moderate-to-severe Psoriasis

Biological drugs targeting tumour necrosis factor are effective for psoriasis. However, 30–50% of patients do not respond to these drugs and may even develop paradoxical psoriasiform reactions. This study search­ed for DNA copy number variations that could predict anti-tumour necrotic factor drug re...

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Bibliographic Details
Main Authors: Ancor Sanz-Garcia, Alejandra Reolid, Laura H. Fisas, Ester Muñoz-Aceituno, Mar Llamas-Velasco, Antonio Sahuquillo-Torralba, Rafael Botella-Estrada, Jorge García-Martínez, Raquel Navarro, Esteban Daudén, Francisco Abad-Santos, Maria C. Ovejero-Benito
Format: Article
Language:English
Published: Society for Publication of Acta Dermato-Venereologica 2021-05-01
Series:Acta Dermato-Venereologica
Subjects:
pharmacogenomic
cnv
psoriasis
anti-tnf drug
methylation
Online Access: https://www.medicaljournals.se/acta/content/html/10.2340/00015555-3794

Internet

https://www.medicaljournals.se/acta/content/html/10.2340/00015555-3794

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