Phylogenetics Applied to Genotype/Phenotype Association and Selection Analyses with Sequence Data from Angptl4 in Humans

Phylogenetics Applied to Genotype/Phenotype Association and Selection Analyses with Sequence Data from Angptl4 in Humans

Genotype/phenotype association analyses (Treescan) with plasma lipid levels and functional site prediction methods (TreeSAAP and PolyPhen) were performed using sequence data for ANGPTL4 from 3,551 patients in the Dallas Heart Study. Biological assays of rare variants in phenotypic tails and results...

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Bibliographic Details
Main Authors: Todd Jarvis, Jeffrey Staples, Matthew L. Bendall, Taylor J. Maxwell, Keith A. Crandall
Format: Article
Language:English
Published: MDPI AG 2010-01-01
Series:International Journal of Molecular Sciences
Subjects:
ANGPTL4
TreeSAAP
treescan
phylogenetics
association studies
selection
Online Access:http://www.mdpi.com/1422-0067/11/1/370/

Internet

http://www.mdpi.com/1422-0067/11/1/370/

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