GO-PROMTO illuminates protein membrane topologies of glycan biosynthetic enzymes in the Golgi apparatus of living tissues.

The Golgi apparatus is the main site of glycan biosynthesis in eukaryotes. Better understanding of the membrane topology of the proteins and enzymes involved can impart new mechanistic insights into these processes. Publically available bioinformatic tools provide highly variable predictions of memb...

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Bibliographic Details
Main Authors: Casper Søgaard, Anne Stenbæk, Sophie Bernard, Masood Hadi, Azeddine Driouich, Henrik Vibe Scheller, Yumiko Sakuragi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3283625?pdf=render