Myocardial connective tissue growth factor (CCN2/CTGF) attenuates left ventricular remodeling after myocardial infarction.

AIMS: Myocardial CCN2/CTGF is induced in heart failure of various etiologies. However, its role in the pathophysiology of left ventricular (LV) remodeling after myocardial infarction (MI) remains unresolved. The current study explores the role of CTGF in infarct healing and LV remodeling in an anima...

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Bibliographic Details
Main Authors: Jørgen Gravning, Stein Ørn, Ole Jørgen Kaasbøll, Vladimir N Martinov, Cord Manhenke, Kenneth Dickstein, Thor Edvardsen, Håvard Attramadal, Mohammed Shakil Ahmed
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3527406?pdf=render