Dynamic behaviors of α-synuclein and tau in the cellular context: New mechanistic insights and therapeutic opportunities in neurodegeneration
α-Synuclein (αS) and tau have a lot in common. Dyshomeostasis and aggregation of both proteins are central in the pathogenesis of neurodegenerative diseases: Parkinson's disease, dementia with Lewy bodies, multi-system atrophy and other ‘synucleinopathies’ in the case of αS; Alzheimer's di...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2019-12-01
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Series: | Neurobiology of Disease |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0969996119302116 |