Redox regulation of protein nanomechanics in health and disease: Lessons from titin

The nanomechanics of sarcomeric proteins is a key contributor to the mechanical output of muscle. Among them, titin emerges as a main target for the regulation of the stiffness of striated muscle. In the last years, single-molecule experiments by Atomic Force Microscopy (AFM) have demonstrated that...

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Bibliographic Details
Main Authors: Elías Herrero-Galán, Inés Martínez-Martín, Jorge Alegre-Cebollada
Format: Article
Language:English
Published: Elsevier 2019-02-01
Series:Redox Biology
Online Access:http://www.sciencedirect.com/science/article/pii/S221323171830939X