Prime-boost with Mycobacterium smegmatis recombinant vaccine improves protection in mice infected with Mycobacterium tuberculosis.

The development of a new vaccine as a substitute for Bacillus Calmette-Guerin or to improve its efficacy is one of the many World Health Organization goals to control tuberculosis. Mycobacterial vectors have been used successfully in the development of vaccines against tuberculosis. To enhance the p...

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Bibliographic Details
Main Authors: Ana Paula Junqueira-Kipnis, Fábio Muniz de Oliveira, Monalisa Martins Trentini, Sangeeta Tiwari, Bing Chen, Danilo Pires Resende, Bruna D S Silva, Mei Chen, Lydia Tesfa, William R Jacobs, André Kipnis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3826754?pdf=render