Hepatitis C virus infection causes iron deficiency in Huh7.5.1 cells.

Patients with chronic hepatitis C virus (HCV) infection frequently develop systemic iron overload, which exacerbates morbidity. Nevertheless, iron inhibits HCV replication in cell culture models and thereby exerts antiviral activity. We hypothesized that the cellular iron status is crucial for the e...

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Bibliographic Details
Main Authors: Carine Fillebeen, Kostas Pantopoulos
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3862679?pdf=render