Mitochondrial DNA sequence variation and haplogroup distribution in Chinese patients with LHON and m.14484T>C.

Mitochondrial DNA sequence variation and haplogroup distribution in Chinese patients with LHON and m.14484T>C.

<h4>Background</h4>Leber hereditary optic neuropathy (LHON, MIM 535000) is one of the most common mitochondrial genetic disorders caused by three primary mtDNA mutations (m.3460G>A, m.11778G>A and m. 14484T>C). The clinical expression of LHON is affected by many additional facto...

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Bibliographic Details
Main Authors: Dandan Yu, Xiaoyun Jia, A-Mei Zhang, Shiqiang Li, Yang Zou, Qingjiong Zhang, Yong-Gang Yao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-10-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20976138/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20976138/?tool=EBI

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