Lichen secondary metabolites in Flavocetraria cucullata exhibit anti-cancer effects on human cancer cells through the induction of apoptosis and suppression of tumorigenic potentials.

Lichen secondary metabolites in Flavocetraria cucullata exhibit anti-cancer effects on human cancer cells through the induction of apoptosis and suppression of tumorigenic potentials.

Lichens are symbiotic organisms which produce distinct secondary metabolic products. In the present study, we tested the cytotoxic activity of 17 lichen species against several human cancer cells and further investigated the molecular mechanisms underlying their anti-cancer activity. We found that a...

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Bibliographic Details
Main Authors: Thanh Thi Nguyen, Somy Yoon, Yi Yang, Ho-Bin Lee, Soonok Oh, Min-Hye Jeong, Jong-Jin Kim, Sung-Tae Yee, Florin Crişan, Cheol Moon, Kwang Youl Lee, Kyung Keun Kim, Jae-Seoun Hur, Hangun Kim
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4216107?pdf=render

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http://europepmc.org/articles/PMC4216107?pdf=render

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