The emerging links between chromosomal instability (CIN), metastasis, inflammation and tumour immunity

Abstract Many cancers possess an incorrect number of chromosomes, a state described as aneuploidy. Aneuploidy is often caused by Chromosomal Instability (CIN), a process of continuous chromosome mis-segregation. CIN is believed to endow tumours with enhanced evolutionary capabilities due to increase...

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Bibliographic Details
Main Authors: Andréa E. Tijhuis, Sarah C. Johnson, Sarah E. McClelland
Format: Article
Language:English
Published: BMC 2019-05-01
Series:Molecular Cytogenetics
Online Access:http://link.springer.com/article/10.1186/s13039-019-0429-1