Heart-derived fibroblasts express LYPD-1 and negatively regulate angiogenesis in rat

Angiogenesis is regulated by a balance between promoting and inhibitory mechanisms. Although angiogenesis-promoting mechanisms have been well studied in ischemic heart diseases, angiogenesis-inhibitory mechanisms have not. Recently, we identified LYPD-1 as a novel anti-angiogenic factor derived from...

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Bibliographic Details
Main Authors: Satoru Sakamoto, Katsuhisa Matsuura, Shinako Masuda, Nobuhisa Hagiwara, Tatsuya Shimizu
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:Regenerative Therapy
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S235232042030033X