X Chromosome Crossover Formation and Genome Stability in Caenorhabditis elegans Are Independently Regulated by xnd-1

X Chromosome Crossover Formation and Genome Stability in Caenorhabditis elegans Are Independently Regulated by xnd-1

The germ line efficiently combats numerous genotoxic insults to ensure the high fidelity propagation of unaltered genomic information across generations. Yet, germ cells in most metazoans also intentionally create double-strand breaks (DSBs) to promote DNA exchange between parental chromosomes, a pr...

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Bibliographic Details
Main Authors: T. Brooke McClendon, Rana Mainpal, Francis R. G. Amrit, Michael W. Krause, Arjumand Ghazi, Judith L. Yanowitz
Format: Article
Language:English
Published: Oxford University Press 2016-12-01
Series:G3: Genes, Genomes, Genetics
Subjects:
meiosis
ATM
Tip60
ionizing radiation
genome instability
Online Access:http://g3journal.org/lookup/doi/10.1534/g3.116.035725

Internet

http://g3journal.org/lookup/doi/10.1534/g3.116.035725

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