Dual function of the nuclear export signal of the Borna disease virus nucleoprotein in nuclear export activity and binding to viral phosphoprotein

Dual function of the nuclear export signal of the Borna disease virus nucleoprotein in nuclear export activity and binding to viral phosphoprotein

Abstract Background Borna disease virus (BoDV), which has a negative-sense, single-stranded RNA genome, causes persistent infection in the cell nucleus. The nuclear export signal (NES) of the viral nucleoprotein (N) consisting of leucine at positions 128 and 131 and isoleucine at positions 133 and 1...

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Bibliographic Details
Main Authors: Mako Yanai, Madoka Sakai, Akiko Makino, Keizo Tomonaga
Format: Article
Language:English
Published: BMC 2017-07-01
Series:Virology Journal
Subjects:
Borna disease virus
Nucleocytoplasmic shuttling
Nuclear export signal
Nucleoprotein-phosphoprotein interaction
Polymerase activity
Online Access:http://link.springer.com/article/10.1186/s12985-017-0793-6

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http://link.springer.com/article/10.1186/s12985-017-0793-6

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