Differentiation and Expansion of Beta Cell Mass in Porcine Neonatal Pancreatic Cell Clusters Transplanted into Nude Mice

Neonatal porcine pancreas has considerable capacity for growth and differentiation, making it an attractive potential source of islet tissue for xenotransplantation. Pancreases from 1–3-day-old newborn pigs were digested with collagenase and cultured for 8 days. The resulting cellular aggregates are...

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Bibliographic Details
Main Authors: Kun-Ho Yoon, Robert R. Quickel, Krystyna Tatarkiewicz, Thomas R. Ulrich, Jennifer Hollister-Lock, Nitin Trivedi, Susan Bonner-Weir, Gordon C. Weir M.D.
Format: Article
Language:English
Published: SAGE Publishing 1999-11-01
Series:Cell Transplantation
Online Access:https://doi.org/10.1177/096368979900800613