Development of an angiogenesis-promoting microvesicle-alginate-polycaprolactone composite graft for bone tissue engineering applications

One of the major challenges of bone tissue engineering applications is to construct a fully vascularized implant that can adapt to hypoxic environments in vivo. The incorporation of proangiogenic factors into scaffolds is a widely accepted method of achieving this goal. Recently, the proangiogenic p...

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Bibliographic Details
Main Authors: Hui Xie, Zhenxing Wang, Liming Zhang, Qian Lei, Aiqi Zhao, Hongxiang Wang, Qiubai Li, Zhichao Chen, WenJie Zhang
Format: Article
Language:English
Published: PeerJ Inc. 2016-05-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/2040.pdf