Antioxidant Saffron and Central Retinal Function in ABCA4-Related Stargardt Macular Dystrophy

Antioxidant Saffron and Central Retinal Function in ABCA4-Related Stargardt Macular Dystrophy

Retinal oxidative damage, associated with an ATP-binding cassette, sub-family A, member 4, also known as ABCA4 gene mutation, has been implicated as a major underlying mechanism for Stargardt disease/fundus flavimaculatus (STG/FF). Recent findings indicate that saffron carotenoid constituents crocin...

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Bibliographic Details
Main Authors: Marco Piccardi, Antonello Fadda, Francesco Martelli, Dario Marangoni, Adriano Magli, Angelo M. Minnella, Matteo Bertelli, Stefano Di Marco, Silvia Bisti, Benedetto Falsini
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:Nutrients
Subjects:
abca4 gene mutation
antioxidants
focal electroretinogram
neuroprotection
photoreceptors
saffron
retinal function
personalized medicine
Online Access:https://www.mdpi.com/2072-6643/11/10/2461

Internet

https://www.mdpi.com/2072-6643/11/10/2461

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