Multicellular gene network analysis identifies a macrophage-related gene signature predictive of therapeutic response and prognosis of gliomas

Multicellular gene network analysis identifies a macrophage-related gene signature predictive of therapeutic response and prognosis of gliomas

Abstract Background The tumor-associated microenvironment plays important roles in tumor progression and drug resistance. However, systematic investigations of macrophage–tumor cell interactions to identify novel macrophage-related gene signatures in gliomas for predicting patient prognoses and resp...

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Bibliographic Details
Main Authors: Xiaoqiang Sun, Xiaoping Liu, Mengxue Xia, Yongzhao Shao, Xiaohua Douglas Zhang
Format: Article
Language:English
Published: BMC 2019-05-01
Series:Journal of Translational Medicine
Subjects:
Multicellular gene network
Macrophages
Prognostic signature
Drug resistance
Glioma
Biomarker
Online Access:http://link.springer.com/article/10.1186/s12967-019-1908-1

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http://link.springer.com/article/10.1186/s12967-019-1908-1

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