XRCC1 gene polymorphisms in a population sample and in women with a family history of breast cancer from Rio de Janeiro (Brazil)

XRCC1 gene polymorphisms in a population sample and in women with a family history of breast cancer from Rio de Janeiro (Brazil)

The X-ray repair cross-complementing Group1 (XRCC1) gene has been defined as essential in the base excision repair (BER) and single-strand break repair processes. This gene is highly polymorphic, and the most extensively studied genetic changes are in exon 6 (Arg194Trp) and in exon 10 (Arg399Gln). T...

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Bibliographic Details
Main Authors: Priscila Falagan-Lotsch, Marina S. Rodrigues, Viviane Esteves, Roberto Vieira, Luis C. Amendola, Dante Pagnoncelli, Júlio C. Paixão, Claudia V. De Moura Gallo
Format: Article
Language:English
Published: Sociedade Brasileira de Genética 2009-01-01
Series:Genetics and Molecular Biology
Subjects:
XRCC1 gene polymorphisms
breast cancer susceptibility
Brazilian population
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572009000200008

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572009000200008

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