Gint4.T-Modified DNA Tetrahedrons Loaded with Doxorubicin Inhibits Glioma Cell Proliferation by Targeting PDGFRβ

Gint4.T-Modified DNA Tetrahedrons Loaded with Doxorubicin Inhibits Glioma Cell Proliferation by Targeting PDGFRβ

Abstract Glioma is one of the deadliest intrinsic brain tumours due to its invasive growth. The effect of glioma treatment is poor because of the presence of the blood-brain barrier and blood tumour barrier and insufficient drug targeting. DNA tetrahedrons (TDN) show great potential for drug deliver...

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Bibliographic Details
Main Authors: Feng Wang, Yanghao Zhou, Si Cheng, Jinhe Lou, Xiang Zhang, Qiuguang He, Ning Huang, Yuan Cheng
Format: Article
Language:English
Published: SpringerOpen 2020-07-01
Series:Nanoscale Research Letters
Subjects:
Glioma
Platelet-derived growth factor receptor β
Gint4.T
DNA tetrahedron
Nanostructures
Online Access:http://link.springer.com/article/10.1186/s11671-020-03377-y

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http://link.springer.com/article/10.1186/s11671-020-03377-y

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