Roles of Dom34:Hbs1 in Nonstop Protein Clearance from Translocators for Normal Organelle Protein Influx

Roles of Dom34:Hbs1 in Nonstop Protein Clearance from Translocators for Normal Organelle Protein Influx

Because messenger RNAs without a stop codon (nonstop mRNAs) generate stalled ribosomes, cells have developed a mechanism allowing degradation of nonstop mRNAs and their translation products (nonstop proteins) in the cytosol. Here, we observe the fate of nonstop proteins destined for organelles such...

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Bibliographic Details
Main Authors: Toshiaki Izawa, Tatsuhisa Tsuboi, Kazushige Kuroha, Toshifumi Inada, Shuh-ichi Nishikawa, Toshiya Endo
Format: Article
Language:English
Published: Elsevier 2012-09-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124712002355

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http://www.sciencedirect.com/science/article/pii/S2211124712002355

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